diff --git a/spring-boot-project/spring-boot-test/src/main/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizer.java b/spring-boot-project/spring-boot-test/src/main/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizer.java
index 027f75eae1..73312c4adb 100644
--- a/spring-boot-project/spring-boot-test/src/main/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizer.java
+++ b/spring-boot-project/spring-boot-test/src/main/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizer.java
@@ -16,6 +16,7 @@
 
 package org.springframework.boot.test.web.client;
 
+import org.springframework.aot.AotDetector;
 import org.springframework.beans.BeansException;
 import org.springframework.beans.factory.BeanFactory;
 import org.springframework.beans.factory.BeanFactoryAware;
@@ -103,6 +104,9 @@ class TestRestTemplateContextCustomizer implements ContextCustomizer {
 
 		@Override
 		public void postProcessBeanDefinitionRegistry(BeanDefinitionRegistry registry) throws BeansException {
+			if (AotDetector.useGeneratedArtifacts()) {
+				return;
+			}
 			if (BeanFactoryUtils.beanNamesForTypeIncludingAncestors((ListableBeanFactory) this.beanFactory,
 					TestRestTemplate.class, false, false).length == 0) {
 				registry.registerBeanDefinition(TestRestTemplate.class.getName(),
diff --git a/spring-boot-project/spring-boot-test/src/test/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizerTests.java b/spring-boot-project/spring-boot-test/src/test/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizerTests.java
index 7f5217f0ea..bb754700a7 100644
--- a/spring-boot-project/spring-boot-test/src/test/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizerTests.java
+++ b/spring-boot-project/spring-boot-test/src/test/java/org/springframework/boot/test/web/client/TestRestTemplateContextCustomizerTests.java
@@ -1,5 +1,5 @@
 /*
- * Copyright 2012-2021 the original author or authors.
+ * Copyright 2012-2022 the original author or authors.
  *
  * Licensed under the Apache License, Version 2.0 (the "License");
  * you may not use this file except in compliance with the License.
@@ -23,6 +23,7 @@ import org.springframework.beans.factory.support.DefaultListableBeanFactory;
 import org.springframework.boot.test.context.SpringBootTest;
 import org.springframework.boot.test.context.SpringBootTest.WebEnvironment;
 import org.springframework.boot.test.context.runner.ApplicationContextRunner;
+import org.springframework.context.ConfigurableApplicationContext;
 import org.springframework.context.support.AbstractApplicationContext;
 import org.springframework.test.context.MergedContextConfiguration;
 
@@ -38,13 +39,24 @@ import static org.mockito.Mockito.mock;
 class TestRestTemplateContextCustomizerTests {
 
 	@Test
-	@SuppressWarnings({ "unchecked", "rawtypes" })
 	void whenContextIsNotABeanDefinitionRegistryTestRestTemplateIsRegistered() {
-		new ApplicationContextRunner(TestApplicationContext::new).withInitializer((context) -> {
-			MergedContextConfiguration configuration = mock(MergedContextConfiguration.class);
-			given(configuration.getTestClass()).willReturn((Class) TestClass.class);
-			new TestRestTemplateContextCustomizer().customizeContext(context, configuration);
-		}).run((context) -> assertThat(context).hasSingleBean(TestRestTemplate.class));
+		new ApplicationContextRunner(TestApplicationContext::new)
+				.withInitializer(this::applyTestRestTemplateContextCustomizer)
+				.run((context) -> assertThat(context).hasSingleBean(TestRestTemplate.class));
+	}
+
+	@Test
+	void whenUsingAotGeneratedArtifactsTestRestTemplateIsNotRegistered() {
+		new ApplicationContextRunner().withSystemProperties("spring.aot.enabled:true")
+				.withInitializer(this::applyTestRestTemplateContextCustomizer)
+				.run((context) -> assertThat(context).doesNotHaveBean(TestRestTemplate.class));
+	}
+
+	@SuppressWarnings({ "unchecked", "rawtypes" })
+	void applyTestRestTemplateContextCustomizer(ConfigurableApplicationContext context) {
+		MergedContextConfiguration configuration = mock(MergedContextConfiguration.class);
+		given(configuration.getTestClass()).willReturn((Class) TestClass.class);
+		new TestRestTemplateContextCustomizer().customizeContext(context, configuration);
 	}
 
 	@SpringBootTest(webEnvironment = WebEnvironment.RANDOM_PORT)