diff --git a/spring-boot-project/spring-boot-test-autoconfigure/src/main/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfiguration.java b/spring-boot-project/spring-boot-test-autoconfigure/src/main/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfiguration.java
index 1a839e95f0..1d1959a065 100644
--- a/spring-boot-project/spring-boot-test-autoconfigure/src/main/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfiguration.java
+++ b/spring-boot-project/spring-boot-test-autoconfigure/src/main/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfiguration.java
@@ -24,6 +24,7 @@ import javax.sql.DataSource;
 import org.apache.commons.logging.Log;
 import org.apache.commons.logging.LogFactory;
 
+import org.springframework.aot.AotDetector;
 import org.springframework.beans.BeansException;
 import org.springframework.beans.factory.FactoryBean;
 import org.springframework.beans.factory.InitializingBean;
@@ -83,6 +84,9 @@ public class TestDatabaseAutoConfiguration {
 
 		@Override
 		public void postProcessBeanDefinitionRegistry(BeanDefinitionRegistry registry) throws BeansException {
+			if (AotDetector.useGeneratedArtifacts()) {
+				return;
+			}
 			Assert.isInstanceOf(ConfigurableListableBeanFactory.class, registry,
 					"Test Database Auto-configuration can only be used with a ConfigurableListableBeanFactory");
 			process(registry, (ConfigurableListableBeanFactory) registry);
diff --git a/spring-boot-project/spring-boot-test-autoconfigure/src/test/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfigurationTests.java b/spring-boot-project/spring-boot-test-autoconfigure/src/test/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfigurationTests.java
index cf494a2fd7..550a8909a9 100644
--- a/spring-boot-project/spring-boot-test-autoconfigure/src/test/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfigurationTests.java
+++ b/spring-boot-project/spring-boot-test-autoconfigure/src/test/java/org/springframework/boot/test/autoconfigure/jdbc/TestDatabaseAutoConfigurationTests.java
@@ -21,6 +21,7 @@ import javax.sql.DataSource;
 import org.junit.jupiter.api.Test;
 
 import org.springframework.boot.autoconfigure.AutoConfigurations;
+import org.springframework.boot.test.autoconfigure.jdbc.TestDatabaseAutoConfiguration.EmbeddedDataSourceFactoryBean;
 import org.springframework.boot.test.context.runner.ApplicationContextRunner;
 import org.springframework.context.annotation.Bean;
 import org.springframework.context.annotation.Configuration;
@@ -49,6 +50,7 @@ class TestDatabaseAutoConfigurationTests {
 	@Test
 	void replaceWithUniqueDatabase() {
 		this.contextRunner.withUserConfiguration(ExistingDataSourceConfiguration.class).run((context) -> {
+			assertThat(context).hasSingleBean(EmbeddedDataSourceFactoryBean.class);
 			DataSource datasource = context.getBean(DataSource.class);
 			JdbcTemplate jdbcTemplate = new JdbcTemplate(datasource);
 			jdbcTemplate.execute("create table example (id int, name varchar);");
@@ -60,6 +62,13 @@ class TestDatabaseAutoConfigurationTests {
 		});
 	}
 
+	@Test
+	void whenUsingAotGeneratedArtifactsEmbeddedDataSourceFactoryBeanIsNotDefined() {
+		this.contextRunner.withUserConfiguration(ExistingDataSourceConfiguration.class)
+				.withSystemProperties("spring.aot.enabled=true")
+				.run((context) -> assertThat(context).doesNotHaveBean(EmbeddedDataSourceFactoryBean.class));
+	}
+
 	@Configuration(proxyBeanMethods = false)
 	static class ExistingDataSourceConfiguration {