diff --git a/spring-integration-core/src/main/java/org/springframework/integration/config/DefaultConfiguringBeanFactoryPostProcessor.java b/spring-integration-core/src/main/java/org/springframework/integration/config/DefaultConfiguringBeanFactoryPostProcessor.java
index a1cc2c3f08..c943677845 100644
--- a/spring-integration-core/src/main/java/org/springframework/integration/config/DefaultConfiguringBeanFactoryPostProcessor.java
+++ b/spring-integration-core/src/main/java/org/springframework/integration/config/DefaultConfiguringBeanFactoryPostProcessor.java
@@ -38,6 +38,7 @@ import org.springframework.beans.factory.SmartInitializingSingleton;
 import org.springframework.beans.factory.config.BeanDefinition;
 import org.springframework.beans.factory.config.BeanDefinitionHolder;
 import org.springframework.beans.factory.config.BeanFactoryPostProcessor;
+import org.springframework.beans.factory.config.ConfigurableBeanFactory;
 import org.springframework.beans.factory.config.ConfigurableListableBeanFactory;
 import org.springframework.beans.factory.config.PropertiesFactoryBean;
 import org.springframework.beans.factory.config.RuntimeBeanReference;
@@ -517,6 +518,8 @@ class DefaultConfiguringBeanFactoryPostProcessor
 		if (!this.beanFactory.containsBean(IntegrationContextUtils.MESSAGE_HANDLER_FACTORY_BEAN_NAME)) {
 			BeanDefinitionBuilder messageHandlerMethodFactoryBuilder =
 					createMessageHandlerMethodFactoryBeanDefinition(false);
+			// TODO: https://github.com/spring-projects/spring-framework/issues/23352
+			messageHandlerMethodFactoryBuilder.setScope(ConfigurableBeanFactory.SCOPE_PROTOTYPE);
 			this.registry.registerBeanDefinition(IntegrationContextUtils.MESSAGE_HANDLER_FACTORY_BEAN_NAME,
 					messageHandlerMethodFactoryBuilder.getBeanDefinition());
 		}
@@ -526,6 +529,8 @@ class DefaultConfiguringBeanFactoryPostProcessor
 		if (!this.beanFactory.containsBean(IntegrationContextUtils.LIST_MESSAGE_HANDLER_FACTORY_BEAN_NAME)) {
 			BeanDefinitionBuilder messageHandlerMethodFactoryBuilder =
 					createMessageHandlerMethodFactoryBeanDefinition(true);
+			// TODO: https://github.com/spring-projects/spring-framework/issues/23352
+			messageHandlerMethodFactoryBuilder.setScope(ConfigurableBeanFactory.SCOPE_PROTOTYPE);
 			this.registry.registerBeanDefinition(IntegrationContextUtils.LIST_MESSAGE_HANDLER_FACTORY_BEAN_NAME,
 					messageHandlerMethodFactoryBuilder.getBeanDefinition());
 		}
diff --git a/spring-integration-core/src/test/java/org/springframework/integration/handler/support/MessagingMethodInvocableHelperTests.java b/spring-integration-core/src/test/java/org/springframework/integration/handler/support/MessagingMethodInvocableHelperTests.java
new file mode 100644
index 0000000000..58741a9a32
--- /dev/null
+++ b/spring-integration-core/src/test/java/org/springframework/integration/handler/support/MessagingMethodInvocableHelperTests.java
@@ -0,0 +1,94 @@
+/*
+ * Copyright 2019 the original author or authors.
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+package org.springframework.integration.handler.support;
+
+import static org.assertj.core.api.Assertions.assertThat;
+
+import java.util.Collections;
+import java.util.Map;
+
+import org.junit.jupiter.api.Test;
+
+import org.springframework.beans.factory.annotation.Autowired;
+import org.springframework.context.annotation.Bean;
+import org.springframework.context.annotation.Configuration;
+import org.springframework.integration.channel.QueueChannel;
+import org.springframework.integration.config.EnableIntegration;
+import org.springframework.integration.dsl.IntegrationFlow;
+import org.springframework.integration.handler.GenericHandler;
+import org.springframework.messaging.Message;
+import org.springframework.messaging.MessageHeaders;
+import org.springframework.messaging.support.GenericMessage;
+import org.springframework.test.annotation.DirtiesContext;
+import org.springframework.test.context.junit.jupiter.SpringJUnitConfig;
+
+/**
+ * @author Gary Russell
+ * @since 5.2
+ *
+ */
+@SpringJUnitConfig
+@DirtiesContext
+public class MessagingMethodInvocableHelperTests {
+
+	@Autowired
+	private Config config;
+
+	@Test
+	void cachedHandler() {
+		this.config.sampleFlow().getInputChannel().send(new GenericMessage<>(Collections.singletonMap("key", "value")));
+		Message<?> received = this.config.queue().receive(0);
+		assertThat(received).isNotNull();
+		assertThat(received.getPayload()).isEqualTo("Hello value World!");
+	}
+
+	@Configuration
+	@EnableIntegration
+	public static class Config {
+
+		@Bean
+		public IntegrationFlow sampleFlow() {
+			return f -> f
+					.handle(new MapHandler())
+					.handle(new StringHandler())
+					.channel(queue());
+		}
+
+		@Bean
+		public QueueChannel queue() {
+			return new QueueChannel();
+		}
+
+		public static class MapHandler implements GenericHandler<Map<String, String>> {
+
+			@Override
+			public String handle(Map<String, String> mapPayload, MessageHeaders messageHeaders) {
+				return "Hello " + mapPayload.get("key");
+			}
+		}
+
+		public static class StringHandler implements GenericHandler<String> {
+
+			@Override
+			public String handle(String stringPayload, MessageHeaders messageHeaders) {
+				return stringPayload + " World!";
+			}
+		}
+
+	}
+
+}