diff --git a/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntity.java b/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntity.java
index c54e5399..37b19e5c 100644
--- a/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntity.java
+++ b/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntity.java
@@ -18,6 +18,11 @@ package org.springframework.vault.repository.mapping;
 import org.springframework.data.keyvalue.core.mapping.BasicKeyValuePersistentEntity;
 import org.springframework.data.keyvalue.core.mapping.KeySpaceResolver;
 import org.springframework.data.util.TypeInformation;
+import org.springframework.expression.Expression;
+import org.springframework.expression.ParserContext;
+import org.springframework.expression.common.LiteralExpression;
+import org.springframework.expression.spel.standard.SpelExpressionParser;
+import org.springframework.lang.Nullable;
 import org.springframework.util.StringUtils;
 
 /**
@@ -30,9 +35,13 @@ public class BasicVaultPersistentEntity<T> extends
 		BasicKeyValuePersistentEntity<T, VaultPersistentProperty> implements
 		VaultPersistentEntity<T> {
 
-	private final String keyspace;
+	private static final SpelExpressionParser PARSER = new SpelExpressionParser();
 
-	private final String secretBackend;
+	private final @Nullable String backend;
+	private final @Nullable Expression backendExpression;
+
+	private final @Nullable String keyspace;
+	private final @Nullable Expression keyspaceExpression;
 
 	/**
 	 * Creates new {@link BasicVaultPersistentEntity}.
@@ -46,26 +55,55 @@ public class BasicVaultPersistentEntity<T> extends
 
 		Secret annotation = findAnnotation(Secret.class);
 
-		String keyspace = super.getKeySpace();
-		String secretBackend = "secret";
+		if (annotation != null && StringUtils.hasText(annotation.backend())) {
 
-		if (annotation != null) {
-			if (StringUtils.hasText(annotation.backend())) {
-				secretBackend = annotation.backend();
-			}
+			this.backend = annotation.backend();
+			this.backendExpression = detectExpression(this.backend);
+
+			this.keyspace = super.getKeySpace();
+			this.keyspaceExpression = detectExpression(this.keyspace);
 		}
+		else {
+			this.backend = "secret";
+			this.backendExpression = null;
 
-		this.secretBackend = secretBackend;
-		this.keyspace = String.format("%s/%s", secretBackend, keyspace);
+			this.keyspace = super.getKeySpace();
+			this.keyspaceExpression = null;
+		}
+	}
+
+	/**
+	 * Returns a SpEL {@link Expression} if the given {@link String} is actually an
+	 * expression that does not evaluate to a {@link LiteralExpression} (indicating that
+	 * no subsequent evaluation is necessary).
+	 *
+	 * @param potentialExpression can be {@literal null}
+	 * @return
+	 */
+	@Nullable
+	private static Expression detectExpression(String potentialExpression) {
+
+		Expression expression = PARSER.parseExpression(potentialExpression,
+				ParserContext.TEMPLATE_EXPRESSION);
+		return expression instanceof LiteralExpression ? null : expression;
 	}
 
 	@Override
 	public String getKeySpace() {
-		return keyspace;
+		return String.format("%s/%s", getSecretBackend(), doGetKeySpace());
+	}
+
+	private String doGetKeySpace() {
+		return keyspaceExpression == null //
+		? keyspace //
+				: keyspaceExpression.getValue(getEvaluationContext(null), String.class);
 	}
 
 	@Override
 	public String getSecretBackend() {
-		return secretBackend;
+
+		return backendExpression == null //
+		? backend //
+				: backendExpression.getValue(getEvaluationContext(null), String.class);
 	}
 }
diff --git a/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/Secret.java b/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/Secret.java
index e9c1b800..8cd6e7ed 100644
--- a/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/Secret.java
+++ b/spring-vault-core/src/main/java/org/springframework/vault/repository/mapping/Secret.java
@@ -40,14 +40,17 @@ import org.springframework.data.keyvalue.annotation.KeySpace;
 public @interface Secret {
 
 	/**
-	 * The prefix to distinguish between domain types.
+	 * The prefix to distinguish between domain types. The attribute supports SpEL
+	 * expressions to dynamically calculate the keyspace based on a per-operation basis.
+	 *
 	 * @see KeySpace
 	 */
 	@AliasFor(annotation = KeySpace.class, attribute = "value")
 	String value() default "";
 
 	/**
-	 * Secret backend mount, defaults to {@literal secret}.
+	 * Secret backend mount, defaults to {@literal secret}. The attribute supports SpEL
+	 * expressions to dynamically calculate the backend based on a per-operation basis.
 	 */
 	String backend() default "secret";
 }
diff --git a/spring-vault-core/src/test/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntityUnitTests.java b/spring-vault-core/src/test/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntityUnitTests.java
index 6010a28b..6f33df4d 100644
--- a/spring-vault-core/src/test/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntityUnitTests.java
+++ b/spring-vault-core/src/test/java/org/springframework/vault/repository/mapping/BasicVaultPersistentEntityUnitTests.java
@@ -15,9 +15,15 @@
  */
 package org.springframework.vault.repository.mapping;
 
+import java.util.Collections;
+import java.util.LinkedHashMap;
+import java.util.Map;
+
 import org.junit.Test;
 
 import org.springframework.data.annotation.Id;
+import org.springframework.data.spel.ExtensionAwareEvaluationContextProvider;
+import org.springframework.data.spel.spi.EvaluationContextExtension;
 
 import static org.assertj.core.api.Assertions.assertThat;
 
@@ -48,6 +54,21 @@ public class BasicVaultPersistentEntityUnitTests {
 		assertThat(persistentEntity.getIdProperty()).isNotNull();
 	}
 
+	@Test
+	public void shouldEvaluateExpression() {
+
+		VaultPersistentEntity<?> persistentEntity = mappingContext
+				.getPersistentEntity(ExpressionEntity.class);
+
+		persistentEntity
+				.setEvaluationContextProvider(new ExtensionAwareEvaluationContextProvider(
+						Collections.singletonList(new SampleExtension())));
+
+		assertThat(persistentEntity.getSecretBackend()).isEqualTo("collectionName");
+
+		assertThat(persistentEntity.getKeySpace()).isEqualTo("collectionName/foo");
+	}
+
 	static class IdProperty {
 		String id, username;
 	}
@@ -57,4 +78,26 @@ public class BasicVaultPersistentEntityUnitTests {
 		String username;
 	}
 
+	@Secret(backend = "#{myProperty}", value = "#{myKeySpace}")
+	static class ExpressionEntity {
+		@Id
+		String username;
+	}
+
+	static class SampleExtension implements EvaluationContextExtension {
+
+		@Override
+		public String getExtensionId() {
+			return "sampleExtension";
+		}
+
+		@Override
+		public Map<String, Object> getProperties() {
+
+			Map<String, Object> properties = new LinkedHashMap<>();
+			properties.put("myProperty", "collectionName");
+			properties.put("myKeySpace", "foo");
+			return properties;
+		}
+	}
 }
diff --git a/src/main/asciidoc/new-features.adoc b/src/main/asciidoc/new-features.adoc
index e8f31872..ef0601a0 100644
--- a/src/main/asciidoc/new-features.adoc
+++ b/src/main/asciidoc/new-features.adoc
@@ -4,6 +4,7 @@
 [[new-features.2-2-0]]
 === What's new in Spring Vault 2.2
 * Support for Key-Value v2 (versioned backend) secrets through `@VaultPropertySource`.
+* SpEL support in `@Secret`.
 
 [[new-features.2-1-0]]
 === What's new in Spring Vault 2.1